News and Events

Current Headlines

Drs. Petros Grivas, Mark Day, Maha Hussain
from left to right: Drs. Petros Grivas, Mark Day and Maha Hussain
Bladder cancer is a common cancer that can be fatal and has not benefited from therapeutic advances over two decades. Researchers at the University of Michigan Translational Oncology Program (T.O.P) were able to generate important preclinical data demonstrating the significant activity of a next-generation compound in human models of bladder cancer. This compound, which is also being tested in patients with lung cancer, inhibits biologic pathways that are considered involved in the development and progression of bladder cancer. The data, recently published at "Molecular Medicine" by Drs. Petros Grivas, Maha Hussain, Mark Day and several colleagues, have supported the design of a clinical trial that aims to evaluate the safety of this compound in combination with chemotherapy (gemcitabine/cisplatin) in patients with advanced bladder cancer. This will be the first trial to assess the activity of this inhibitor in patients with this disease, and evaluate its combination with this specific chemotherapy regimen in humans. This is a characteristic example of the mission, vision and goals of the T.O.P., which was created to effectively bridge the gap between the laboratory and the clinic leading to better treatments for the cancer patient.

Links to news articles, videos and radio interviews about the Translational Oncology Research Program (TOP)

Video

Diane Simeone, MD, Lazar J. Greenfield Professor of Surgery and Professor of Molecular & Integrative Physiology and Chief, Division of Hepatopancreatobiliary and Advanced Gastrointestinal Surgery at the University of Michigan gives an overview of pancreatic cancergoing to a new website including treatment research in the area of stem cells, presented at the AACR 2012 Annual Meeting in Chicago.

This video presentation is also available thanks to OncologyTube.com: http://www.oncologytube.com/index.php?page=videos§ion=view&vid_id=102669

Cancer Stem Cells - Max Wicha, MDgoing to a new website
Max Wicha, MD, Director of the University of Michigan Comprehensive Cancer Center discusses cancer stem cell research

The Future of Pancreatic Cancer Treatmentgoing to a new website
Dr. Simeone's appearance on the Dr. Oz show (article with video).

Cancer stem cells: New frontier in cancer researchgoing to a new website
Taubman Institute Health Science Lecture Series. March 2013.

Cancer Stem Cell Research Introduction
from mcancer.org, cancer stem cell tutorial with video.

Innovative Researcher Profile: Dr. Elizabeth R. Lawlorgoing to a new website
Elizabeth R. Lawlor, MD, PhD, Associate Professor, Department of Pathology and Associate Professor, Department of Pediatrics and Communicable Diseases is profiled on the Stand Up to Cancer YouTube channel.

Radio

Curelaunchers and Meals to Healgoing to a new website
Stupid Cancer Show: The voice of young adult cancer. BlogTalkRadio.com. 21 January 2013.

from WIBW.com:
An article with radio interview featuring the work of Mark S. Cohen, M.D., Associate Professor of Surgery and Director of Endocrine Surgery Research: Plant-Based Molecules Show Cancer-Fighting Potentialgoing to a new website

Rob Stein. Lab Findings Support Provocative Theory On Cancer 'Enemy' Withingoing to a new website
All Things Considered, National Public Radio. 01 August 2012 (article and radio interview).

News Articles

Tomatillo plant shows promise in cancer treatment
LJWorld.com

Researchers hope prairie's wild tomatillo may provide medical breakthrough in cancer fightgoing to a new website
Witchita Eagle Kansas.com

Tomatillo: Cancer-fighting potential?going to a new website
Topeka Capital-Journal cjonline.com

Compounds in the Wild Tomatillo Weed May Combat Cancergoing to a new website
Indian Country Today Media Network

Dr. Elizabeth Lawlor, M.D. Ph.D. � University of Michigangoing to a new website
Go4theGoal

Grant Awarded to Scientist Investigating Cancerous Cell Survival in Childrengoing to a new website
CureSearchforChildren'sCancer

News Articles from University of Michigan publications

U-M Cancer Center gets $28.4 million grant from NCI
mcancer.org website. 31 October, 2012.

NCRC Momentum Website Octobergoing to a new website

Diane Simeone to head translational oncology program at NCRCgoing to a new website

Speeding Promising Discoveries to Clinical Trialsgoing to a new website

Inflammatory pathway spurs cancer stem cells to resist HER2-targeted breast cancer treatment

Translational oncology establishes presence at NCRC: Dr. Max Wicha and researchers move their labsgoing to a new website

Return to top