News and Events
Current HeadlinesBladder cancer is a common cancer that can be fatal and has not benefited from therapeutic advances over two decades. Researchers at the University of Michigan Translational Oncology Program (T.O.P) were able to generate important preclinical data demonstrating the significant activity of a next-generation compound in human models of bladder cancer. This compound, which is also being tested in patients with lung cancer, inhibits biologic pathways that are considered involved in the development and progression of bladder cancer. The data, recently published at "Molecular Medicine" by Drs. Petros Grivas, Maha Hussain, Mark Day and several colleagues, have supported the design of a clinical trial that aims to evaluate the safety of this compound in combination with chemotherapy (gemcitabine/cisplatin) in patients with advanced bladder cancer. This will be the first trial to assess the activity of this inhibitor in patients with this disease, and evaluate its combination with this specific chemotherapy regimen in humans. This is a characteristic example of the mission, vision and goals of the T.O.P., which was created to effectively bridge the gap between the laboratory and the clinic leading to better treatments for the cancer patient.
Links to news articles, videos and radio interviews about the Translational Oncology Research Program (TOP)
VideoDiane Simeone, MD, Lazar J. Greenfield Professor of Surgery and Professor of Molecular & Integrative Physiology and Chief, Division of Hepatopancreatobiliary and Advanced Gastrointestinal Surgery at the University of Michigan gives an overview of pancreatic cancer including treatment research in the area of stem cells, presented at the AACR 2012 Annual Meeting in Chicago.
This video presentation is also available thanks to OncologyTube.com: http://www.oncologytube.com/index.php?page=videos§ion=view&vid_id=102669
Cancer Stem Cells - Max Wicha, MD
Max Wicha, MD, Director of the University of Michigan Comprehensive Cancer Center discusses cancer stem cell research
The Future of Pancreatic Cancer Treatment
Dr. Simeone's appearance on the Dr. Oz show (article with video).
Cancer stem cells: New frontier in cancer research
Taubman Institute Health Science Lecture Series. March 2013.
Cancer Stem Cell Research Introduction
from mcancer.org, cancer stem cell tutorial with video.
Innovative Researcher Profile: Dr. Elizabeth R. Lawlor
Elizabeth R. Lawlor, MD, PhD, Associate Professor, Department of Pathology and Associate Professor, Department of Pediatrics and Communicable Diseases is profiled on the Stand Up to Cancer YouTube channel.
Curelaunchers and Meals to Heal
Stupid Cancer Show: The voice of young adult cancer. BlogTalkRadio.com. 21 January 2013.
An article with radio interview featuring the work of Mark S. Cohen, M.D., Associate Professor of Surgery and Director of Endocrine Surgery Research: Plant-Based Molecules Show Cancer-Fighting Potential
Lab Findings Support Provocative Theory On Cancer 'Enemy' Within
All Things Considered, National Public Radio. 01 August 2012 (article and radio interview).
News ArticlesTomatillo plant shows promise in cancer treatment
Researchers hope prairie's wild
tomatillo may provide medical breakthrough in cancer fight
Witchita Eagle Kansas.com
Tomatillo: Cancer-fighting potential?
Topeka Capital-Journal cjonline.com
Compounds in the Wild Tomatillo Weed May Combat Cancer
Indian Country Today Media Network
Grant Awarded to Scientist Investigating
Cancerous Cell Survival in Children
News Articles from University of Michigan publications
U-M Cancer Center gets $28.4 million grant from NCI
mcancer.org website. 31 October, 2012.