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Cancer's Stem Cell Revolution:
Identifying stem cells

To identify stem cells, scientists use specialized equipment to detect specific proteins on the cell's surface

How do scientists identify cancer stem cells?
Watch as Max Wicha, M.D., Director of the Comprehensive Cancer Center, explains how stem cells are identified

Even under a microscope, there's no way to distinguish cancer stem cells from other malignant cells just by looking at them. To identify stem cells, scientists use specialized equipment to detect specific proteins on the cell's surface. These proteins are not found on regular cancer cells.

To prove that cells with certain protein markers are cancer stem cells, scientists use a special test. They inject cells from a human tumor into mice that are genetically engineered to lack a cancer-fighting immune system. If the mouse does not get cancer, scientists know the injected cells were not stem cells, because ordinary tumor cells will divide a few times and then die. But if the mouse develops a tumor with the same types of cells as the human tumor, scientists know that the injected cells were true cancer stem cells.

Continue on to page 2 of "Identifying Stem Cells"

 

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Read more about research on specific cancer stem cells:
Stem Cells in Breast Cancer

Stem Cells in Pancreatic Cancer

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