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National Functional Genomics Center at the UMCCC

Supported Cores

In addition to the three main projects and pilot studies, the NFGC will establish four core facilities offering specialized services to the UMCCC research community in RNAi technologies, mouse xenograft production and modeling, bioinformatics and research administration.

The RNAi core under the direction of Dr. Gabe Nunez will utilize high-throughput siRNA screening to identify new regulatory genes involved in cancer progression.

The Xenograft Core, under the direction of Dr. Diane Simeone, will establish xenograft models that recapitulate human disease and afford researchers the opportunity to test new hypotheses regarding cancer stem cells therapeutics. The Bioinformatics Core will provide a team of biostatisticians skilled in research project development and analysis of results to facilitate preparation of bioinformatics data for interpretation, publication and presentation.

The Administrative Core will provide scientific oversight, encourage communication with collaborators and serve as a liaison between other NFGC sites, institutional leaders and the sponsor assuring compliance with all University requirements as well as those of the sponsor.