| originally
posted as part of U-M CCC in the News on April 28, 2001
ANN ARBOR, Mich. – The University
of Michigan Comprehensive Cancer Center announces the appointment
of Daniel F. Hayes, M.D., as the new clinical director of
its Breast Oncology Program.
Hayes,
who also serves as a professor in the Department of Internal
Medicine of the U-M Medical School, will be responsible for
directing clinical services and overseeing the translation
of basic breast cancer research into clinical trials. He comes
to the U-M from Georgetown
University.
Specifically, Hayes will focus the program's
efforts on:
- further integrating scientific endeavors within the Breast
Oncology Program, which receives one of the nation's highest
levels of government funding for research
- increasing collaborations with the Department of Radiology
to enhance screening and monitoring of breast cancer patients
- developing new techniques for cancer screening and chemoprevention
(e.g., ductal lavage)
- continued research aimed at gene identification and care
of women at high risk of developing breast cancer
- developing innovative clinical trials aimed at improving
primary and systemic treatments for newly diagnosed patients
(e.g. cryoablation
- testing new drugs for advanced breast cancer (e.g., therapies
directed toward the EGFR family)
- identifying molecular targets for breast cancer and developing
novel compounds to test against them; and
- addressing quality of life issues for survivors (e.g.
antidepressants for hot flashes).
"Dr. Hayes is one the leading experts in developing
new treatments for breast cancer patients based on the translation
of laboratory science into the clinic," says Max S. Wicha,
M.D., director of the U-M Cancer Center and Distinguished
Professor of Oncology. "We are delighted to have been able
to attract him to Michigan to lead our efforts in this area,
helping to further develop what is now one of the strongest
breast cancer programs in the nation."
Over nearly 20 years, Hayes' professional training
and career have been directed toward bridging the gap between
laboratory and clinical research. He received a bachelor's
degree (1974) in biology and a master's degree (1977) in biochemistry
at Indiana University. He received his M.D. from the Indiana
University School of Medicine in 1979, followed by a residency
in internal medicine at the University of Texas Health Science
Center at Dallas.
Hayes served a fellowship in medical oncology
from 1982 to 1985 at Harvard's Dana Farber Cancer Institute
(DFCI) in Boston. In 1992, he assumed the role as the medical
director of the Breast Evaluation Center at DFCI. In 1996
Hayes moved to Georgetown University and spent the succeeding
five years collaborating with Marc E. Lippman, M.D., a world-renowned
breast cancer expert who also recently joined the University
of Michigan, as chair of the Department of Internal Medicine.
Hayes has been influential in both clinical
and laboratory studies of the diagnosis and treatment of breast
cancer. With his long-time colleague, Donald Kufe, Hayes published
the first reports concerning the development of the CA15-3
blood test, which is currently used worldwide to evaluate
patients with breast cancer. He has become an internationally
recognized leader in the use of this and other tumor markers,
such as HER-2, specifically for breast cancer but also for
other cancers. He is widely considered to be an expert in
the field of clinical research on breast cancer, particularly
in the areas of new hormonal and chemotherapeutic treatments.
He also lectures and publishes extensively regarding the management
of breast cancer patients.
Reflecting his expertise, Hayes has served as
Chair of the Solid Tumor Correlative Sciences Committee of
the Cancer and Leukemia Group B (CALGB), one of the leading
federally funded, multi-institutional, cooperative groups
that perform definitive clinical research in cancer care.
He has also been a core member and past vice-chair of the
Breast Cancer Committee of the CALGB. He serves on the Expert
Panel for Tumor Marker Practice Guidelines for the American
Society of Clinical Oncology, and he is on the editorial boards
of several leading cancer journals.
Hayes lives in Ann Arbor, Michigan, with his
wife Jane and their two sons, Benjamin and Stephen, who are
both pursuing post-secondary education.
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