Research Programs
Gastrointestinal Oncology SPORE
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Our clinic provides people diagnosed with breast cancer a
team-based approach to treatment.
Project 1
Project 2
Project 3
Neilson AP, Djuric Z, Ren J, Jiang J, Reuven S, Lager C, Hong YH, Sen A, Smith WL, Brenner DE.
Effect of cyclooxygenase genotype and dietary fish oil on colonic eicosanoids in mice.
J Nutri Biochem, In press, 2011. "PMC Journal-In Process".
Effect of cyclooxygenase genotype and dietary fish oil on colonic eicosanoids in mice.
J Nutri Biochem, In press, 2011. "PMC Journal-In Process".
Project 2
Lin, Z., D. Simeone, M. Anderson, R. Brand, X. Xie, K. Shedden, M. Ruffin, D. Lubman.
A Mass Spectrometric Assay for Analysis of Haptoglobin Fucosylation in Pancreatic Cancer.
Journal of Proteome Research 2011, 2011 May 6;10(5):2602-11. Epub 2011 Mar 31. NIHMSID#284125 PMCID: PMC3090531[Available on 2012/5/6]
A Mass Spectrometric Assay for Analysis of Haptoglobin Fucosylation in Pancreatic Cancer.
Journal of Proteome Research 2011, 2011 May 6;10(5):2602-11. Epub 2011 Mar 31. NIHMSID#284125 PMCID: PMC3090531[Available on 2012/5/6]
Project 3
Parsels, L.A., Qian, Y, Tanska, D.M., et al.
Assessment of Chk1 phosphorylation as a pharmacodynamic biomarker of Chk1 inhibition
Clin Cancer Res. 2011 Jun 1;17(11):3706-15.
Epub 2011 Apr 11. PMCID: PMC3107893[Available on 2012/6/1]
Assessment of Chk1 phosphorylation as a pharmacodynamic biomarker of Chk1 inhibition
Clin Cancer Res. 2011 Jun 1;17(11):3706-15.
Epub 2011 Apr 11. PMCID: PMC3107893[Available on 2012/6/1]
Zhao, L., Morgan, M.A., Parsels, L.A., et al.
Bayesian Hierarchical Changepoint Methods in Modeling the Tumor Growth Profiles in Xenograft Experiments.
Clin Cancer Res 2011;17:1057-1064.
PMCID: PMC3048927[Available on 2012/3/1]
Project 4Bayesian Hierarchical Changepoint Methods in Modeling the Tumor Growth Profiles in Xenograft Experiments.
Clin Cancer Res 2011;17:1057-1064.
PMCID: PMC3048927[Available on 2012/3/1]
Wang L, Heidt DG, Lee CJ, Logsdon CD, Zhang L, Fearon ER, Ljungman ME, Simeone DM.
Oncogenic function of ATDC (TRIM 29) in pancreatic cancer
through Wnt pathway activation and ?-catenin stabilization.
Cancer Cell 2009; 15: 207-219. PMCID: PMC2673547
Cancer Cell 2009; 15: 207-219. PMCID: PMC2673547
Lee CJ, Spalding A, Ben-Josef E, Wang L, Simeone DM.
In vivo bioluminescent imaging of radiated orthotopic pancreatic xenografts in NOD/SCID mice: a novel method for assaying clinical efficacy of ionizing radiation.
Translational Oncology 2010; 3: 153-159. PMCID: PMC2887644
In vivo bioluminescent imaging of radiated orthotopic pancreatic xenografts in NOD/SCID mice: a novel method for assaying clinical efficacy of ionizing radiation.
Translational Oncology 2010; 3: 153-159. PMCID: PMC2887644
Manuscripts in Preparation
Wang L, Yang H, Davis M, Krueger H, Canman C, Xu L, Ljungman M, Simeone DM. ATDC (TRIM29) participates in the radiation-induced DNA damage response.
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