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Natural History and Signs and Symptoms

Signs and Symptoms

  • Early-stage disease

  • Advanced disease

 

Early-stage disease

Men with organ-confined prostate cancer often are have no detectable symptoms related to their prostate cancer. Men with an enlarged prostate can have urinary symptoms (frequency or slowstreams) that are usually not caused by their prostate cancer.

 

Advanced disease

Urinary symptoms can be a sign of locally advanced prostate cancer. A few men with locally advanced disease present with hematuria, urinary tract infections, and irritative voiding symptoms secondary to bladder outlet obstruction.

Rarely, men with metastatic prostate cancer can develop bone pain or leg swelling, weakness or (rarely) paralysis.

 

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