Home >
Cancer and Treatments > Prostate Cancer >
Prostate Cancer Information > Prostate Cancer Education
> Treatment > Advanced systemic disease
Radiotherapy is very effective in controlling local
pain associated with skeletal prostate metastasis. In general,
a treatment regimen of 30 Gy over 10 treatments results in
rapid and durable local symptom control and a reduced dependence
on analgesics.
For patients with more extensive bone involvement
causing pain that may be practically difficult to address
with localized external-beam techniques, alternatives include
wide-field irradiation (ie, hemibody radiation) or systemic
administration of radioactive bone-seeking isotopes that can
deliver therapeutic doses to skeletal metastatic disease.
Radioactive isotopes used in this fashion include strontium-89
chloride (Metastron) and samarium SM 153 lexidronam (Quadramet).
