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BMT Success Stories

Duncan Darnell

Photo caption: Dr. Jamie Ferrara with Duncan

Duncan Darnell of Lansing was one year old when he was diagnosed with a rare and deadly form of bone marrow cancer called juvenile myelomonocytic leukemia. His best chance for a cure was a bone marrow transplant which he received at the University of Michigan Mott Children’s Hospital in September.

The bone marrow from Duncan’s identical twin brother, Craig, was a perfect genetic match, but it couldn’t be used because Craig’s immune system was unlikely to eliminate Duncan’s leukemia. We were able to locate a suitable unrelated volunteer donor whose bone marrow was more likely to do the job, but the procedure was risky because it carries a high probability of graft versus host disease (GVHD), a potentially lethal complication. To increase his chances of success, Duncan participated in a clinical trial to prevent GVHD that is available only to University of Michigan patients. Two months have now passed since his transplant without any signs of GVHD – so far, so good!

Duncan’s mother, Ella, says that he enjoys the books in the playroom when he visits for his follow-up treatment. Duncan has also taken a real shining to several of his UM caregivers. “The doctors and staff definitely convey a personal touch during our visits,” says Ella. Bubbles are a big hit too!

 

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