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Hodgkin's Disease

Definition

Hodgkin's lymphoma (also called Hodgkin's disease) is a cancer that starts in the lymph system. The lymph system includes the lymph nodes, lymph vessels, and other parts of the body's immune and blood-forming systems, such as the spleen and bone marrow. The lymph system makes, stores, and carries infection-fighting white blood cells called lymphocytes. Lymph nodes and lymph vessels are located throughout the body.

Lymphoma is the third most common cancer in children in the United States. Approximately 10 percent of cancers in children less than 15 years of age are lymphomas.

Hodgkin's disease rarely arises before the age of 5. It almost always develops in lymph nodes and often spreads to adjacent lymph node areas. When it is no longer confined to lymph nodes, it may spread to the spleen, liver, lungs, bones and bone marrow.

Getting Diagnosed / Treatment

Hodgkin's Disease, also called Hodgkin's Lymphoma is treated in the Pediatric Hematology Oncology Clinic.

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What are the symptoms?

Symptoms depend on where the lymphoma is located. The lymph nodes most often involved are those in the neck, underarms and groin. These nodes become large, firm and are usually not painful. Enlarged lymph nodes may also be located in the chest and produce a cough or breathing problems. Some children develop night sweats, fever and weight loss. If Hodgkin's disease is suspected, it is important that a complete evaluation for sites of disease occur in order to establish extent of spread.

How is lymphoma treated?

The likelihood of cure is related to the extent of disease. Surgery is beneficial to establish a diagnosis. chemotherapy, radiation or a combination of the two is necessary. It is very important that children with suspected Hodgkin's disease be cared for at a hospital with specialists in children's cancer care, such as the University of Michigan.

How can I get more information about lymphoma?

Telephone our Cancer AnswerLine at 800-865-1125 or e-mail a nurse.

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This site is part of the U-M Health System. The information presented is not a tool for self diagnosis or a substitute for professional care. © 2008 U-M Comprehensive Cancer Center