Home > Cancer and Treatments > Pancreatic Cancer > Research
> Publications
Articles by Diane Simeone, M.D.
click on the authors to view .pdf documents
Chen J, Anderson M, Misek DE, Simeone DM, Lubman DM.
Characterization of apolipoprotein and apolipoprotein precursors in pancreatic cancer serum samples via two-dimensional liquid chromatography and mass spectrometry.
J Chromatogr A. 2007 Aug 31;1162(2):117-25. Epub 2007 Mar 30.
PMID: 17434173 [Pub Med -in process]
Dalerba P, Dylla SJ, Park IK, Liu R, Wang X, Cho RW, Hoey T, Gurney A, Huang EH, Simeone DM, Shelton AA, Parmiani G, Castelli C, Clarke MF.
Phenotypic characterization of human colorectal cancer stem cells.
Proc Natl Acad Sci U S A. 2007 Jun 12;104(24):10158-63. Epub 2007 Jun 4.
PMID: 17548814 [Pub Med indexed for MEDLINE]
Zhao J, Patwa TH, Qiu W, Shedden K, Hinderer R, Misek DE, Anderson MA, Simeone DM, Lubman DM.
Glycoprotein microarrays with multi-lectin detection: unique lectin binding patterns as a tool for classifying normal, chronic pancreatitis and pancreatic cancer sera.
J Proteome Res. 2007 May;6(5):1864-74. Epub 2007 Apr 12.
PMID: 17428079 [Pub Med indexed for MEDLINE]
Chen S, LaRoche T, Hamelinck D, Bergsma D, Brenner D, Simeone D, Brand RE, Haab BB.
Multiplexed analysis of glycan variation on native proteins captured by antibody microarrays.
Nat Methods. 2007 May;4(5):437-44. Epub 2007 Apr 8.
PMID: 17417647 [Pub Med indexed for MEDLINE]
Simeone DM, Ji B, Banerjee M, Arumugam T, Li D, Anderson MA, Bamberger AM, Greenson J, Brand RE, Ramachandran V, Logsdon CD.
CEACAM1, a novel serum biomarker for pancreatic cancer.
Pancreas. 2007 May;34(4):436-43.
PMID: 17446843 [Pub Med indexed for MEDLINE]
Huang EH, Heidt DG, Li CW, Simeone DM.
Cancer stem cells: a new paradigm for understanding tumor progression and therapeutic resistance.
Surgery. 2007 Apr;141(4):415-9. Review. No abstract available.
PMID: 17383517 [Pub Med indexed for MEDLINE]
Ramachandran V, Arumugam T, Hwang RF, Greenson JK, Simeone DM, Logsdon CD.
Adrenomedullin is expressed in pancreatic cancer and stimulates cell proliferation and invasion in an autocrine manner via the adrenomedullin receptor, ADMR.
Cancer Res. 2007 Mar 15;67(6):2666-75.
PMID: 17363587 [Pub Med indexed for MEDLINE]
Zhao J, Qiu W, Simeone DM, Lubman DM.
N-linked glycosylation profiling of pancreatic cancer serum using capillary liquid phase separation coupled with mass spectrometric analysis.
J Proteome Res. 2007 Mar;6(3):1126-38. Epub 2007 Jan 24.
PMID: 17249709 [Pub Med indexed for MEDLINE]
Li C, Heidt DG, Dalerba P, Burant CF, Zhang L, Adsay V, Wicha M, Clarke MF, Simeone DM.
Identification of pancreatic cancer stem cells.
Cancer Res. 2007 Feb 1;67(3):1030-7.
PMID: 17283135 [Pub Med indexed for MEDLINE]
Heidt DG, Burant C, Simeone DM.
Total pancreatectomy: indications, operative technique, and postoperative sequelae.
J Gastrointest Surg. 2007 Feb;11(2):209-16.
PMID: 17390175 [Pub Med In process]
Simeone DM, Zhang L, Treutelaar MK, Zhang L, Graziano K, Logsdon CD, Burant CF.
Islet hypertrophy following pancreatic disruption of Smad4 signaling.
Am J Physiol Endocrinol Metab. 2006 Dec;291(6):E1305-16. Epub 2006 May 30
PMID: 16735447 [Pub Med indexed for MEDLINE]
Yoo C, Zhao J, Pal M, Hersberger K, Huber CG, Simeone DM, Beer DG, Lubman DM.
Automated integration of monolith-based protein separation with on-plate
digestion for mass spectrometric analysis of esophageal adenocarcinoma human epithelial samples.
Electrophoresis. 2006 Sep;27(18):3643-51.
PMID: 16927349 [Pub Med in process]
Patwa TH, Zhao J, Anderson MA, Simeone DM, Lubman DM.
Screening of Glycosylation Patterns in Serum Using Natural
Glycoprotein Microarrays and Multi-Lectin Fluorescence Detection.
Anal Chem. 2006 Sep 15; 78(18):6411-21.
PMID: 16970316 [Pub Med in process]
Zhao J, Simeone DM, Heidt D, Anderson MA, Lubman DM.
Comparative Serum Glycoproteomics Using Lectin Selected Sialic Acid Glycoproteins with Mass Spectrometric Analysis: Application to Pancreatic Cancer Serum.
J Proteome Res. 2006 Jul;5(7):1792-802.
PMID: 16823988 [Pub Med - indexed for MEDLINE].
Newman EA, Simeone DM, Mulholland MW.
Adjuvant Treatment Strategies for Pancreatic Cancer.
J Gastrointest Surg. 2006 Jun;10(6):916-26.
PMID: 16769552 [Pub Med - in process].
Simeone DM, Zhang L, Treutelaar MK, Zhang L, Graziano K, Logsdon CD, Burant CF.
Islet Hypertrophy Following Pancreatic Disruption of Smad4 Signaling.
Am J Physiol Endocrinol Metab. 2006 May 30; [Epub ahead of print]
PMID: 16735447[Pub Med - as supplied by publisher].
Zhang L, Chenwei L, Mahmood R, van Golen K, Greenson J, Li G, D'Silva NJ, Li X, Burant CF, Logsdon CD, Simeone DM.
Identification of a Putative Tumor Suppressor Gene Rap1GAP in Pancreatic Cancer
Cancer Res. 2006 Jan 15;66(2):898-906.
PMID: 16424023 [Pub Med - indexed for MEDLINE].
Arumugam T, Simeone DM, Van Golen K, Logsdon CD.
S100P Promotes Pancreatic Cancer Growth, Survival, and Invasion.
Clin Cancer Res. 2005 Aug 1;11(15):5356-64.
PMID: 16061848 [Pub Med - indexed for MEDLINE].
Binkley CE, Zhang L, Greenson JK, Giordano TJ, Kuick R, Misek D, Hanash S, Logsdon CD, Simeone DM.
The Molecular Basis of Pancreatic Fibrosis.
Pancreas 2004 Nov;29(4):254-63.
PMID: 15502640 [Pub Med - indexed for MEDLINE].
Zhang L, Fu Z, Binkley C, Giordano T, Burant CF, Logsdon CD, Simeone DM.
Raf kinase inhibitory protein inhibits b-cell proliferation.
Surgery. 2004 Sep;136(3):708-15.
PMID: 15349122 [Pub Med - indexed for MEDLINE].
Hong SH, Misek DE, Wang H, Puravs E, Giordano TJ, Greenson JK, Brenner DE, Simeone DM, Logsdon CD, Hanash SM.
An Autoantibody-Mediated Immune Response to Calreticulin Isoforms in Pancreatic Cancer.
Cancer Res. 2004 Aug 1;64(15):5504-10.
PMID: 15289361 [Pub Med - indexed for MEDLINE].
Okami J, Simeone DM, Logsdon CD.
Silencing of the Hypoxia-Inducible Cell Death Protein BNIP3 in Pancreatic Cancer.
Cancer Res. 2004 Aug 1;64(15):5338-46.
PMID: 15289340 [Pub Med - indexed for MEDLINE].
Zhang L, Duan CJ, Binkley C, Li G, Uhler MD, Logsdon CD, Simeone DM.
A Transforming Growth Factor .-Induced Smad3/Smad4 Complex Directly Activates Protein Kinase A.
Mol Cell Biol. 2004 Mar;24(5):2169-80.
PMID: 14966294 [Pub Med - indexed for MEDLINE].
Arumugam T, Simeone DM, Schmidt AM, Logsdon CD.
S100P Stimulates Cell Proliferation and Survival via Receptor for Activated Glycation End Products (RAGE).
J Biol Chem. 2004 Feb 13;279(7):5059-65 Epub 2003 Nov 14.
PMID: 14617629 [Pub Med - indexed for MEDLINE].
Knipp BS, Ailawadi G, Ford JW, Peterson DA, Eagleton MJ, Roelofs KJ, Hannawa KK, Deogracias MP, Ji B, Logsdon C, Graziano KD, Simeone DM, Thompson RW, Henke PK, Stanley JC, Upchurch GR Jr.
Increased MMP-9 Expression and Activity by Aortic Smooth Muscle Cells after Nitric Oxide Synthase Inhibition Is Associated With Increased Nuclear Factor-.B and Activator Protein-1 Activity1.
J Surg Res. 2004 Jan;116(1):70-80.
PMID: 14732351 [Pub Med - indexed for MEDLINE].
Shedden KA, Taylor JA, Giordano TJ, Kuick R, Misek DE, Rennert G, Schwartz DR, Gruber SB, Logsdon C,
Simeone DM, Kardia SL, Greenson JK, Cho KR, Beer DG, Fearon ER, Hanash S
Accurate Molecular Classification of Human Cancers Based on Gene Expression Using a Simple Classifier with a Pathological Tree-Based Framework.
American Journal of Pathology 2003 Nov;163(5):1985-95.
PMID: 14578198. [Pub Med - indexed for MEDLINE].
Treutelaar MK, Skidmore JM, Dias-Leme CL, Hara M, Zhang L, Simeone DM, Martin DM, Burant1 CF.
Nestin-Lineage Cells Contribute to the Microvasculature but Not Endocrine Cells of the Islet
Diabetes 2003 Oct;52(10):2503-12.
PMID: 14514633 [Pub Med - indexed for MEDLINE].
Logsdon CD, Simeone DM, Binkley C, Arumugam T, Greenson JK, Giordano TJ, Misek DE, Kuick R, Hanash S.
Molecular Profiling of Pancreatic Adenocarcinoma and Chronic Pancreatitis Identifies Multiple Genes Differentially Regulated in Pancreatic Cancer.
Cancer Res. 2003 May 15;63(10):2649-57.
PMID: 12750293 [Pub Med - indexed for MEDLINE].
Ji B, Bi Y, Simeone D, Mortensen RM, Logsdon CD.
Human Pancreatic Acinar Cells Do Not Respond to Cholecystokinin.
Pharmacol Toxicol. 2002 Dec;91(6):327-32. Review.
PMID: 12688376 (Pub Med).
Binkley CE, Cinti S, Simeone DM, Colletti LM.
Bacillus Anthracis as an Agent of Bioterrorism.
Ann Surg. 2002 Jul;236(1):9-16
[Pub Med - indexed for MEDLINE].
Burant CF, Simeone DM.
Connecting islet development and developing useful islets.
Trends Endocrinol Metab. 2002 Mar;13(2):48-9.
PMID: 11854014 [Pub Med - indexed for MEDLINE].
Chen X, Ji B, Han B, Ernst SA, Simeone D, Logsdon CD.
NF-kB Activation in Pancreas Induces Pancreatic and Systemic Inflammatory Response.
Gastroenterology 2002 Feb;122(2):448-57.
PMID: 11832459 (Pub Med).
Return to the top of the page
