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About Pancreatic Research

Pancreatic cancer is a most deadly disease characterized by late diagnosis, aggressive invasion of surrounding tissues, and early metastasis. It has the worst prognosis of any major malignancy (3% 5 year survival) and is the fourth most common cause of cancer death. Recent advances in surgical and medical therapy have had little impact on the mortality rate of this disease. Pancreatic cancer is notoriously resistant to many types of cytotoxic chemotherapy and ionizing radiation. The molecular basis of pancreatic cancer is incompletely understood, but the research within the laboratory of Diane Simeone, M.D. is focused to try to understand this terrible disease.

 


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