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Home > Cancer and Treatments > Head & Neck Cancers Salivary Gland CancersDefinitionSalivary gland cancer is a rare disease in which cancer cells form in the tissues of the salivary glands.The salivary glands make saliva and release it into the mouth. There are 3 pairs of major salivary glands:
Parotid glands:
The largest of the salivary glands, located in front of and just below each ear. Most major salivary gland tumors begin in this gland. Sublingual glands: Found under the tongue in the floor of the mouth. Submandibular glands: Located below the jawbone. There are hundreds of minor (small) salivary glands lining parts of the mouth, nose, and larynx that can be seen only with a microscope. Most small salivary gland tumors begin in the roof of the mouth (palate). More than half of all salivary gland tumors are not cancerous (benign) and do not spread to other tissues. Getting Diagnosed / TreatmentThis cancer is treated at the U-M Cancer Center in the Multidisciplinary Head & Neck Cancer Clinic. It may also be treated in Oral and Maxillofacial Surgery.The Head and Neck Oncology Program coordinates research efforts related to salivary gland cancer. Read about:
Risk Factors for Salivary Gland CancerAnything that increases the chance of getting a disease is called a risk factor. Although the cause of most salivary gland cancers is not known, risk factors include the following:
Being exposed to certain types of radiation may increase the risk of salivary cancer.
Older age. Treatment with radiation therapy to the head and neck. Being exposed to certain substances at work. SymptomsSalivary gland cancer may not cause any symptoms. It is sometimes found during a regular dental check-up or physical exam.Symptoms caused by salivary gland cancer also may be caused by other conditions. Consult a doctor should any of the following problems occur:
A lump (usually painless) in the area of the ear, cheek, jaw, lip, or inside the mouth. It may cause difficulty swallowing.
Fluid draining from the ear. Trouble swallowing or opening the mouth widely. Numbness or weakness in the face. Pain in the face that does not go away. DiagnosisThe following procedures may be used:
Because salivary gland cancer can be hard to diagnose, patients should ask to have biopsy samples checked by a pathologist who has experience in diagnosing salivary gland cancer. Treatment OptionsThere are different types of treatment for patients with salivary gland cancer. Some treatments are standard, and some are being tested in clinical trials. Before starting treatment, patients may want to think about taking part in a clinical trial. A treatment clinical trial is a research study meant to help improve current treatments or obtain information on new treatments for patients with cancer. When clinical trials show that a new treatment is better than the standard treatment, the new treatment may become the standard treatment.Three types of standard treatment are used:
Surgery
This is a very common treatment for salivary gland cancer. In some cases, a lymphadenectomy (surgery in which l lymph nodes are removed) will also be done. Even if the doctor removes all the cancer that can be seen at the time of the surgery, some patients may be given radiation therapy after surgery to kill any cancer cells that are left. Treatment given after surgery to increase the chance of a cure is called adjuvant therapy. Radiation therapy Learn more about UMHS Radiation Oncology. Chemotherapy Still have questions?Contact the Cancer AnswerLine through their webpage or at 800-865-1125. |
University of Michigan Comprehensive Cancer Center This site is part of the U-M Health System. The information presented is not a tool for self diagnosis or a substitute for professional care. © 2008 U-M Comprehensive Cancer Center |
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