Prostate Cancer Genetics Project (PCGP)
About UsSince 1995, the University of Michigan Prostate Cancer Genetics Project (PCGP) has been searching for the genetic basis of inherited prostate cancer. We are part of an international consortium of research institutions studying this problem.
Our laboratory researchers process and examine DNA obtained from the blood samples donated by participants. The DNA is obtained from white cells in the blood samples collected from men with prostate cancer and their family members. Human DNA contains approximately 25,000 genes that direct the many functions of the human body.
We suspect that one or more of these genes may contain a variant that contributes to the development of prostate cancer. We have been tracking patterns in DNA sequences suspected to be involved in prostate cancer. By comparing samples from families with multiple cases of prostate cancer, we are closing in on regions of the genome that may contain a prostate cancer susceptibility gene and coming closer to understanding how and why prostate cancer runs in families.