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Cancer's Stem Cell Revolution:
Treatment options with stem cells

Research on cancer stem cells could change everything about how doctors diagnose, prevent and treat cancer

Will the discovery of cancer stem cells change how doctors treat cancer?

By analyzing the genes that are active in a patient's cancer stem cells and counting the number of stem cells in a tumor, physicians could identify patients at high risk for advanced, aggressive disease.
Watch the video and listen as Max Wicha, Director, Comprehensive Cancer Center, explains how stem cells may impact cancer treatment

New therapies designed to target stem cells could eliminate cancer without the risks and side effects of current treatments that also destroy healthy cells in the body. Destroying cancer stem cells in the original tumor could reduce the risk of deadly metastasis, where malignant cells move from the primary tumor to other places in the body. Finally, by killing the cells driving the tumor's growth, treatments targeted at cancer stem cells could eliminate recurrences of the disease.

Why doesn't chemotherapy and radiation kill cancer stem cells?

Scientists don't know for sure. Since chemotherapy and radiation kill cells that divide often, stem cells may be less vulnerable because they rarely divide. Some scientists believe cancer stem cells may have genetic mutations that make them resistant to damage from chemotherapy or radiation, or cancer stem cells may be able to repair DNA damage more rapidly than normal cells.

 

Continue on to page 2 of "Treatment Options with Cancer Stemcells

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This document is not intended to take the place of the care and attention of your personal physician or other professional medical services. Our aim is to promote active participation in your care and treatment by providing information and education. Questions about individual health concerns or specific treatment options should be discussed with your physician.

This information is part of the U-M Health System. The information presented is not a tool for self diagnosis or a substitute for professional care. © 2008 The Regents of the University of Michigan


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Read more about research on specific cancer stem cells:
Stem Cells in Breast Cancer

Stem Cells in Pancreatic Cancer

More resources on stem cells:

Stem cell research at the University of Michigan
Stem Cells - Explained and Explored

National Institutes of Health Web site on stem cells

International Society for Stem Cell Research

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© 2008 Regents of the University of Michigan / Developed & maintained by: Public Relations & Marketing Communications. Contact Us or UMHS. The information presented is not a tool for self diagnosis or a substitute for professional care.