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		Learn more about Dr. Tomlinson's research in the news article Urine test shows prostate cancer risk, U-M study finds Home > Cancer and Treatments > Urologic Cancers > Prostate Cancer Prostate Cancer Awareness Month September is Prostate Cancer Awareness Month Prostate cancer is the most common major cancer diagnosed in men. More than 220,000 cases of prostate cancer will be diagnosed this year in the United States. African American men have higher incidence and at least double the mortality rates compared with men of other racial and ethnic groups. (Source: A Snapshot of Prostate Cancer produced by the National Cancer Institute (NCI) [PDF]. Seventy-nine percent of all prostate cancers are discovered in the local and regional stages; the 5-year relative survival rate for patients whose tumors are diagnosed at these stages is 100%. Over the past 20 years, the survival rate for all stages combined has increased from 67% to 92%. Survival after a diagnosis of prostate cancer continues to decline beyond five years. According to the most recent data, 67% of men diagnosed with prostate cancer survive 10 years and 52% survive 15 years. News U-M News New urine DNA test used with PSA can eliminate unncessary biopsies and reduce fear of overtreatment Men have overly optimistic expectations about recovery from prostate cancer surgery Drug shows promise in prostate cancer spread to the bone Half of prostate cancers could potentially benefit from new type of cancer drugs, U-M study finds Addition of atrasentan to standard chemotherapy for advanced prostate cancer shows no benefit in phase III clinical trial U-M scientists find potential driver of some aggressive prostate cancers Prostate cancer spreads to bones by overtaking the home of blood stem cells Scientists target aggressive prostate cancer Study: Prostate cancer treatment linked to higher rate of colon cancer Gene fusions may be the "smoking gun" in prostate cancer development Researchers discover melanoma drug target that occurs in prostate cancer Genetic markers could predict prostate cancer in younger men Researchers discover metabolite linked to aggressive prostate cancer Study looks at using the immune system to reduce prostate cancer risk Married men more likely to be screened for prostate cancer New, non-invasive prostate cancer test beats PSA in detecting prostate cancer, researchers report U-M researchers discover traits of aggressive form of prostate cancer Type of prostate cancer treatment affects quality of life, multicenter study finds Risk Factors Studies have found the following risk factors for prostate cancer: Age over 65: Age is the main risk factor for prostate cancer. The chance of getting prostate cancer increases as you get older. In the United States, most men with prostate cancer are over 65. This disease is rare in men under 45. Family history: Your risk is higher if your father, brother, or son had prostate cancer. Race: Prostate cancer is more common among black men than white or Hispanic/Latino men. It's less common among Asian/Pacific Islander and American Indian/Alaska Native men. Certain prostate changes: Men with cells called high-grade prostatic intraepithelial neoplasia (PIN) may be at increased risk of prostate cancer. These prostate cells look abnormal under a microscope. Certain genome changes: Researchers have found specific regions on certain chromosomes that are linked to the risk of prostate cancer. According to recent studies, if a man has a genetic change in one or more of these regions, the risk of prostate cancer may be increased. The risk increases with the number of genetic changes that are found. Also, other studies have shown an elevated risk of prostate cancer among men with changes in certain genes, such as BRCA1 and BRCA2. Source: NCI: What You Need to Know™ About Prostate Cancer. Screening American Cancer Society revised prostate cancer screening guidelines: ACS recommends that men with no symptoms of prostate cancer who are in relatively good health and can expect to live at least 10 more years have the opportunity to make an informed decision with their doctor about screening after learning about the uncertainties, risks, and potential benefits associated with prostate cancer screening. These talks should start at age 50. Men with no symptoms who are not expected to live more than 10 years (because of age or poor health) should not be offered prostate cancer screening. Source: American Cancer Society (ACS): Revised Prostate Cancer Screening Guidelines: What Has -- and Hasn't -- Changed Michigan Center for Translational Pathology Screening Information: New urine DNA test and PSA: What you need to know PCA3 Testing Sarcosine and Prostate Cancer Symptoms A man with prostate cancer may not have any symptoms. For men who do have symptoms, the common symptoms include: Urinary problems Not being able to pass urine Having a hard time starting or stopping the urine flow Needing to urinate often, especially at night Weak flow of urine Urine flow that starts and stops Pain or burning during urination Difficulty having an erection Blood in the urine or semen Frequent pain in the lower back, hips, or upper thighs Source: NCI: What You Need to Know™ About Prostate Cancer. Take action Doctors at the U-M Comprehensive Cancer Center are working hard to find better treatments - as well as a cure! -- for cancer, but they can't do it alone. Patients play a vital role in finding better ways to treat cancer by participating in research studies - also known as clinical trials. Learn more about clinical studies. Consider joining a clinical trial! Browse urologic/prostate clinical trials on UMClinicalStudies.org. There are two on-going research projects underway within the Urologic Oncology Program looking for participants: Prostate Cancer Specialized Project of Research Excellence (SPORE) Prostate Cancer Genetics Project National Cancer Institute: Prostate Cancer Clinical Trials Resources University of Michgan Multidisciplinary Urologic Oncology Clinic Department of Urology Radical Prostatectomy Robotic Urologic Surgery (da Vinci) Michigan Center for Translational Pathology Prostate Cancer Education Prostate Cancer, Advanced or Metastastic Prostate Cancer Information Guide Advanced Prostate Information Guide Benign Prostatic Hyperplasia (BPH) Prostate Specific Antigen Screening Prostate Cancer Detection National Resources National Cancer Institute: Prostate Cancer National Cancer Institute: Cancer Advances in Focus, Prostate Cancer National Comprehensive Cancer Network (NCCN) Prostate Cancer, Patient Guidelines PDF Prostate Cancer, localized Prostate Cancer, Advanced Prostate Cancer Foundation National Prostate Cancer Coalition American Cancer Society Detailed Guide - Prostate Cancer Sexuality for the Man with Cancer US Too International Prostate Cancer Education and Support Network Alliance for Prostate Cancer Prevention Return to top of the page		Adjust text size

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